Leu208Val and Ile181Leu variants of cytochrome P450 CYP2C9 are not related to the acenocoumarol dose requirement in a Spanish population

Blood. 2002 Jul 15;100(2):734. doi: 10.1182/blood-2002-03-0821.
No abstract available

Publication types

  • Letter

MeSH terms

  • Acenocoumarol / administration & dosage*
  • Amino Acid Substitution
  • Anticoagulants / administration & dosage
  • Aryl Hydrocarbon Hydroxylases*
  • Cytochrome P-450 CYP2C9
  • Cytochrome P-450 Enzyme System / genetics*
  • Drug Resistance / genetics
  • Genetic Variation*
  • Humans
  • International Normalized Ratio
  • Spain / epidemiology
  • Steroid 16-alpha-Hydroxylase*
  • Steroid Hydroxylases / genetics*

Substances

  • Anticoagulants
  • Cytochrome P-450 Enzyme System
  • Steroid Hydroxylases
  • CYP2C9 protein, human
  • Cytochrome P-450 CYP2C9
  • Aryl Hydrocarbon Hydroxylases
  • Steroid 16-alpha-Hydroxylase
  • Acenocoumarol