Thiopurine S-methyltransferase: a genetic polymorphism that affects a small number of drugs in a big way

Pharmacogenetics. 2002 Aug;12(6):421-3. doi: 10.1097/00008571-200208000-00001.
No abstract available

Publication types

  • Comment

MeSH terms

  • Azathioprine / adverse effects*
  • Colitis, Ulcerative / drug therapy
  • Colitis, Ulcerative / enzymology*
  • Crohn Disease / drug therapy
  • Crohn Disease / enzymology*
  • Genotype
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Methyltransferases / genetics*
  • Methyltransferases / metabolism
  • Neutropenia / chemically induced
  • Phenotype
  • Polymorphism, Genetic*

Substances

  • Immunosuppressive Agents
  • Methyltransferases
  • thiopurine methyltransferase
  • Azathioprine