Zanamivir is an effective treatment for influenza in children undergoing therapy for acute lymphoblastic leukemia

Scand J Infect Dis. 2002;34(8):632-3. doi: 10.1080/00365540210147714.

Abstract

We diagnosed influenza infection in 2 children receiving maintenance treatment for acute lymphoblastic leukemia. Both patients received zanamivir within 1 d of the onset of fever and their symptoms of influenza were rapidly alleviated. We conclude that inhaled zanamivir seems to be an effective treatment for influenza infection in immunocompromised patients.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Antiviral Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Guanidines
  • Humans
  • Influenza, Human / complications
  • Influenza, Human / diagnosis*
  • Influenza, Human / drug therapy*
  • Male
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Pyrans
  • Risk Assessment
  • Sialic Acids / therapeutic use*
  • Treatment Outcome
  • Zanamivir

Substances

  • Antiviral Agents
  • Guanidines
  • Pyrans
  • Sialic Acids
  • Zanamivir