This article provides an overview of the latest theories and technology in compression therapy, and the use of growth factors and skin substitutes. Compression therapy is a major factor in the treatment of venous leg ulcers and is widely used and readily available on the Drug Tariff. Skin substitute and growth factors provide a new technological approach to wound healing with hope for the future management of both acute and chronic wounds. While new technologies are an exciting prospect for the future of wound management, there can be no substitute for good wound care. In the interest of optimum wound management and patient care, health professionals have a duty to find ways to improve patients' quality of life.