Abstract
Recent studies have highlighted the role of inflammatory mediators and the cells of the innate and adaptive immune response in the initiation, growth and rupture of atherosclerotic plaques. Viewing this form of vascular pathology as a modified form of chronic inflammation suggests new avenues for therapeutic intervention in cardiovascular disease.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Animals
-
Anti-Inflammatory Agents / therapeutic use
-
Arteriosclerosis / drug therapy
-
Arteriosclerosis / etiology*
-
Arteriosclerosis / immunology*
-
Arteriosclerosis / pathology
-
Cardiovascular Diseases / etiology
-
Cardiovascular Diseases / immunology
-
Cell Movement
-
Humans
-
Inflammation / etiology
-
Inflammation / immunology
-
Inflammation Mediators / metabolism
-
Leukocytes / immunology
-
Leukocytes / pathology
-
Models, Immunological
Substances
-
Anti-Inflammatory Agents
-
Inflammation Mediators