Superior vena cava syndrome caused by chemotherapy-induced fibrosis

J Chemother. 2002 Aug;14(4):417-9. doi: 10.1179/joc.2002.14.4.417.

Abstract

We report a case of a 51-year old man with small cell lung cancer who developed superior vena cava syndrome due to obstruction of the superior vena cava at the junction of the brachiocephalic vein by a fibrotic band, 2 months after completing six cycles of chemotherapy with cisplatin and etoposid. Superior vena cava syndrome caused by chemotherapy-induced pulmonary fibrosis should be kept in mind during follow-up.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Carcinoma, Small Cell / drug therapy
  • Carcinoma, Small Cell / pathology
  • Cisplatin / administration & dosage
  • Etoposide / administration & dosage
  • Fibrosis
  • Follow-Up Studies
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / pathology
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Superior Vena Cava Syndrome / chemically induced*
  • Superior Vena Cava Syndrome / diagnosis
  • Vena Cava, Superior / drug effects
  • Vena Cava, Superior / pathology*

Substances

  • Etoposide
  • Cisplatin