Hypersexuality after pallidal surgery in Parkinson disease

Neuropsychiatry Neuropsychol Behav Neurol. 2002 Dec;15(4):247-51.

Abstract

Objective: To examine the possible association of neuropsychiatric symptoms and pallidal surgery for Parkinson disease (PD).

Background: Parkinson disease may be accompanied by a variety of psychiatric symptoms. It is important to distinguish these from psychiatric syndromes that are associated with the treatment of PD.

Methods: Case description of a patient with PD and a history of right pallidotomy who developed a psychiatric syndrome, including prominent hypersexuality, after surgical implantation of a deep brain stimulator electrode in the left globus pallidus.

Results and conclusions: This case demonstrates that patients receiving antiparkinson medication may be at risk for the development of psychiatric sequelae after pallidal surgery.

Publication types

  • Case Reports

MeSH terms

  • Antiparkinson Agents / therapeutic use
  • Antipsychotic Agents / therapeutic use
  • Clozapine / therapeutic use
  • Electric Stimulation Therapy
  • Electrodes, Implanted
  • Globus Pallidus / diagnostic imaging
  • Globus Pallidus / physiopathology
  • Globus Pallidus / surgery*
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Neurosurgical Procedures / adverse effects*
  • Parkinson Disease / complications*
  • Parkinson Disease / physiopathology*
  • Parkinson Disease / therapy
  • Sexual Dysfunction, Physiological / diagnosis
  • Sexual Dysfunction, Physiological / drug therapy
  • Sexual Dysfunction, Physiological / etiology*
  • Tomography, X-Ray Computed

Substances

  • Antiparkinson Agents
  • Antipsychotic Agents
  • Clozapine