The enigma of Huntington's disease

Sci Am. 2002 Dec;287(6):92-7. doi: 10.1038/scientificamerican1202-92.
No abstract available

MeSH terms

  • Animals
  • Brain / pathology
  • Brain Chemistry
  • Brain-Derived Neurotrophic Factor / genetics
  • Brain-Derived Neurotrophic Factor / physiology
  • Chromosomes, Human, Pair 4
  • Ciliary Neurotrophic Factor / physiology
  • Glutamine / genetics
  • Humans
  • Huntingtin Protein
  • Huntington Disease / genetics*
  • Huntington Disease / pathology
  • Huntington Disease / therapy
  • Middle Aged
  • Mutation
  • Nerve Tissue Proteins / chemistry
  • Nerve Tissue Proteins / genetics
  • Nerve Tissue Proteins / physiology
  • Nuclear Proteins / chemistry
  • Nuclear Proteins / genetics
  • Nuclear Proteins / physiology
  • Peptides / analysis
  • Peptides / genetics
  • Peptides / metabolism
  • Repetitive Sequences, Nucleic Acid

Substances

  • Brain-Derived Neurotrophic Factor
  • Ciliary Neurotrophic Factor
  • HTT protein, human
  • Huntingtin Protein
  • Nerve Tissue Proteins
  • Nuclear Proteins
  • Peptides
  • Glutamine
  • polyglutamine