Cellular mechanisms of cyclophosphamide resistance: model studies in human medulloblastoma cell lines

Cancer Treat Res. 2002:112:199-209. doi: 10.1007/978-1-4615-1173-1_10.
No abstract available

Publication types

  • Review

MeSH terms

  • Aldehyde Dehydrogenase / metabolism
  • Antineoplastic Agents, Alkylating / therapeutic use*
  • Central Nervous System Neoplasms / drug therapy*
  • Cyclophosphamide / analogs & derivatives*
  • Cyclophosphamide / pharmacology
  • Cyclophosphamide / therapeutic use*
  • DNA / metabolism
  • DNA Repair
  • Drug Resistance, Neoplasm*
  • Glutathione / metabolism
  • Glutathione Transferase / metabolism
  • Humans
  • Medulloblastoma / drug therapy*
  • Models, Chemical
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents, Alkylating
  • Cyclophosphamide
  • DNA
  • Aldehyde Dehydrogenase
  • Glutathione Transferase
  • Glutathione
  • perfosfamide