S-18886 Servier

Curr Opin Investig Drugs. 2002 Sep;3(9):1324-7.

Abstract

S-18886, the active isomer of S-18204, is a thromboxane A2 receptor antagonist with a long duration of action. The compound is under development by Servier for the potential treatment of cardiovascular diseases [269611]. By 2000, a clinical trial had been carried out in patients with coronary artery disease [389458]; advanced clinical trials were ongoing in August 2001 [420310].

Publication types

  • Review

MeSH terms

  • Animals
  • Cardiovascular Diseases / drug therapy
  • Clinical Trials as Topic / methods
  • Clinical Trials as Topic / statistics & numerical data
  • Drug Industry / legislation & jurisprudence*
  • Drug Industry / methods
  • Humans
  • Naphthalenes
  • Propionates
  • Tetrahydronaphthalenes / chemistry
  • Tetrahydronaphthalenes / pharmacology
  • Tetrahydronaphthalenes / therapeutic use*

Substances

  • Naphthalenes
  • Propionates
  • Tetrahydronaphthalenes
  • terutroban