Abstract
We report a fatal case of disseminated adenovirus infection with fulminant hepatic failure in an 8-month-old child after peripheral blood stem cell transplantation. The virus was identified in blood, urine, respiratory aspirate and stool samples and was typed as adenovirus type 2 through PCR and sequencing of part of the hexon gene, with the use of degenerated consensus primers.
MeSH terms
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Adenoviridae Infections / diagnosis*
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Adenoviridae Infections / therapy
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Adenoviruses, Human / isolation & purification*
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DNA, Viral / blood*
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Disease Progression
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Fatal Outcome
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Hematopoietic Stem Cell Transplantation / adverse effects
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Humans
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Infant
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Leukemia, Myelomonocytic, Acute / diagnosis
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Leukemia, Myelomonocytic, Acute / immunology
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Leukemia, Myelomonocytic, Acute / therapy
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Male
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Multiple Organ Failure
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Polymerase Chain Reaction / methods*
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Sensitivity and Specificity
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Severity of Illness Index
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Viremia / diagnosis*
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Viremia / therapy