Dip-pen nanolithography in tapping mode

Gunjan Agarwal; Laura A Sowards; Rajesh R Naik; Morley O Stone

doi:10.1021/ja020471g

Dip-pen nanolithography in tapping mode

J Am Chem Soc. 2003 Jan 15;125(2):580-3. doi: 10.1021/ja020471g.

Authors

Gunjan Agarwal¹, Laura A Sowards, Rajesh R Naik, Morley O Stone

Affiliation

¹ Materials and Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433, USA.

PMID: 12517174
DOI: 10.1021/ja020471g

Abstract

Dip-pen nanolithography (DPN) is becoming a popular nano-patterning technique for depositing materials onto a substrate using the probe of an atomic force microscope (AFM). Here, we demonstrate the deposition of a short synthetic peptide by DPN using the Tapping Mode of AFM rather than the commonly used contact mode. DPN in Tapping Mode requires drive amplitude modifications for deposition, yet allows for gentle imaging of the deposited material and enables deposition on soft surfaces.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Amino Acid Sequence
Microscopy, Atomic Force / methods
Molecular Sequence Data
Nanotechnology / methods*
Peptides / chemistry*

Substances

Peptides