Elevated fecal Candida counts in patients with antibiotic-associated diarrhea: role of soluble fecal substances

Clin Diagn Lab Immunol. 2003 Jan;10(1):167-8. doi: 10.1128/cdli.10.1.167-168.2003.

Abstract

To assess the role of soluble fecal substances in the elevation of fecal Candida counts in patients with antibiotic-associated diarrhea (AAD), we investigated the growth of Candida albicans in vitro in serially diluted stool fluids from patients with AAD and healthy subjects. There were significantly higher Candida albicans counts in stool fluids diluted 1:10 from AAD patients than in healthy subjects and the phosphate-buffered saline growth control, which may be due to reduced soluble Candida inhibitors and increased availability of growth factors and nutrients.

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Candida / growth & development*
  • Candidiasis / etiology
  • Candidiasis / microbiology
  • Case-Control Studies
  • Diarrhea / chemically induced*
  • Feces / microbiology*
  • Humans
  • Solubility

Substances

  • Anti-Bacterial Agents