Study of effect of coal-burning air pollution on children immunity function was hold in Taiyuan city which is one of typical coal-burning air pollution city in China. The children of grade 4-5 who dwell more than 3 years were screened in three different pollution areas. The test includes the observation on the T lymphocyte subpopulations classes (CD3+, CD4+ and CD8+), saliva lysozyme contents and immunoglobulin content. The results showed that the contents of saliva lysozyme and immunoglobulin were lower than those in control area respectively(P < 0.05), and T lymphocyte subpopulations class (the percent ages of CD3+, CD4+ and CD8+) had the same trend, but it was not marked. The results suggested that coal-burning air pollution could affect children by nonspecific immunity and sap immunity. The effect on cell immunity was not marked.