Effects of stress management on PNI-based outcomes in persons with HIV disease

Res Nurs Health. 2003 Apr;26(2):102-17. doi: 10.1002/nur.10074.

Abstract

A pretest-posttest, repeated-measures design was used to evaluate the effects of two stress management interventions on a battery of outcomes derived from a psychoneuroimmunological (PNI) framework. The effects of cognitive-behavioral relaxation training groups (CBSM) and social support groups (SSG) were compared with a WAIT-listed control group on the outcomes of psychosocial functioning, quality of life, neuroendocrine mediation, and somatic health. Participants were 148 individuals (119 men, 29 women), diagnosed with HIV disease; 112 (76%) completing the study groups. Using analysis of covariance, the CBSM group was found to have significantly higher postintervention emotional well-being and total quality-of-life scores than did either the SSG or WAIT groups. SSG participants had significantly lower social/family well-being scores immediately postintervention and lower social support scores after 6 months. The findings point to a pressing need for further, well-controlled research with these common intervention modalities.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adaptation, Psychological
  • Adult
  • Analysis of Variance
  • Dehydroepiandrosterone / metabolism
  • Female
  • HIV Infections / immunology*
  • HIV Infections / psychology*
  • Health Status
  • Humans
  • Hydrocortisone / metabolism
  • Male
  • Mid-Atlantic Region
  • Models, Psychological
  • Psychoneuroimmunology
  • Relaxation Therapy*
  • Stress, Psychological / etiology
  • Stress, Psychological / immunology*
  • Stress, Psychological / prevention & control*

Substances

  • Dehydroepiandrosterone
  • Hydrocortisone