Inflammation and adaptive immune responses to adenoviral vectors injected into the brain: peculiarities, mechanisms, and consequences

Gene Ther. 2003 Jun;10(11):946-54. doi: 10.1038/sj.gt.3302048.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adenoviridae / genetics*
  • Adenoviridae Infections / immunology*
  • Animals
  • Antigens, Viral / immunology
  • Brain / immunology*
  • Cytokines / immunology
  • Encephalitis / immunology*
  • Encephalitis / virology
  • Genetic Therapy / adverse effects*
  • Genetic Vectors / administration & dosage
  • Genetic Vectors / immunology*
  • Humans
  • Injections, Intraventricular
  • T-Lymphocytes / immunology
  • Viral Envelope Proteins / immunology

Substances

  • Antigens, Viral
  • Cytokines
  • Viral Envelope Proteins