Objective: To present a case of one-step total hysteroscopic myomectomy using prostaglandin F(2alpha).
Design: Case report.
Setting: University hospital.
Patient(s): A 38-year-old woman with a sessile submucous leiomyoma.
Intervention(s): Hysteroresectoscopy using an intraoperative injection of prostaglandin F(2alpha) under laparoscopic monitoring.
Main outcome measures: Endoscopic appearance, clinical symptoms, and imaging diagnosis.
Result(s): After resection of the protruding portion of the myoma, injection of prostaglandin F(2alpha) was used to cause the remnant to project into the uterine cavity, allowing complete removal.
Conclusion(s): Intraoperative use of prostaglandin F(2alpha) may allow one-step hysteroresectoscopy of a sessile submucous leiomyoma.