Antigenicity of synthetic peptides derived from C100 protein of hepatitis C virus

Arch Virol Suppl. 1992:4:186-90. doi: 10.1007/978-3-7091-5633-9_39.

Abstract

Synthetic octapeptides spanning the 119-147 region of the Hepatitis C Virus (HCV) C100 protein were tested on HCV positive sera. The 138-145 region proved to be antigenic and possibly able to avoid undesired cross-reactions.

Publication types

  • Comparative Study

MeSH terms

  • Amino Acid Sequence
  • Antigens, Viral / immunology*
  • Cross Reactions
  • Epitopes / immunology
  • Hepacivirus / immunology*
  • Hepatitis Antibodies / blood*
  • Humans
  • Molecular Sequence Data
  • Oligopeptides / immunology*
  • Structure-Activity Relationship
  • Viral Nonstructural Proteins*
  • Viral Proteins / immunology*

Substances

  • Antigens, Viral
  • C100 protein, hepatitis C virus
  • Epitopes
  • Hepatitis Antibodies
  • Oligopeptides
  • Viral Nonstructural Proteins
  • Viral Proteins