Abstract
Most proteins have been formed by gene duplication, recombination, and divergence. Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Binding Sites
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Catalysis
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Computational Biology
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Enzymes / chemistry*
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Enzymes / genetics*
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Enzymes / metabolism
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Evolution, Molecular*
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Gene Duplication
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Genome
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Humans
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Metabolism
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Mutation
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Protein Structure, Tertiary
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Proteins / chemistry*
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Proteins / genetics*
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Proteins / metabolism
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Recombination, Genetic
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Substrate Specificity