Phragmalin limonoids from the Madagascan Meliaceae Neobeguea leandreana

Philip H Coombes; Dulcie A Mulholland; Milijaona Randrianarivelojosia

doi:10.1021/np020481v

Phragmalin limonoids from the Madagascan Meliaceae Neobeguea leandreana

J Nat Prod. 2003 Jun;66(6):735-8. doi: 10.1021/np020481v.

Authors

Philip H Coombes¹, Dulcie A Mulholland, Milijaona Randrianarivelojosia

Affiliation

¹ Natural Products Research Group, School of Pure and Applied Chemistry, University of Natal, Durban 4041, South Africa. coombesp@nu.ac.za

PMID: 12828453
DOI: 10.1021/np020481v

Abstract

The combined hexane-CH(2)Cl(2) extract of the stembark of the Madagascan Meliaceae Neobeguea leandreana yielded three novel phragmalin limonoids, leandreanins A (1), B (2), and C (3). Leandreanins A (1) and B (2) are rare seco-ring D 17-keto compounds related to pseudrelone B, while leandreanin C (3) has an unprecedented acetoxy functionality at C-19.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Limonins / chemistry
Limonins / isolation & purification*
Madagascar
Meliaceae / chemistry*
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Bark / chemistry
Plant Stems / chemistry

Substances

Limonins