Glucocerebrosidase level in the cerebrospinal fluid during enzyme replacement therapy--unsuccessful treatment of the neurological abnormality in type 2 Gaucher disease

Eur J Pediatr. 2003 Jul;162(7-8):524-525. doi: 10.1007/s00431-001-0859-7. Epub 2003 Apr 23.

Authors

Makoto Migita^{1

2}, Hisamitsu Hamada¹, Juri Fujimura¹, Atsushi Watanabe², Takashi Shimada², Yoshitaka Fukunaga¹

Affiliations

¹ Department of Paediatrics, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan, Japan.
² Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan, Japan.

PMID: 12845529
DOI: 10.1007/s00431-001-0859-7

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Female
Gaucher Disease / drug therapy*
Glucosylceramidase / administration & dosage
Glucosylceramidase / blood
Glucosylceramidase / cerebrospinal fluid*
Glucosylceramidase / therapeutic use*
Humans
Infant
Recombinant Proteins / administration & dosage
Recombinant Proteins / blood
Recombinant Proteins / therapeutic use*
Treatment Failure

Substances

Recombinant Proteins
Glucosylceramidase
imiglucerase