Selective incorporation of 19F-labeled Trp side chains for NMR-spectroscopy-based ligand-protein interaction studies

Chembiochem. 2003 Jul 7;4(7):649-50. doi: 10.1002/cbic.200300597.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Escherichia coli / drug effects
  • Escherichia coli / genetics
  • Escherichia coli / metabolism
  • Escherichia coli Proteins / genetics
  • Escherichia coli Proteins / metabolism*
  • Fluorine / chemistry*
  • Hydrocarbons, Fluorinated / chemistry
  • Hydrocarbons, Fluorinated / metabolism
  • Indoles / chemistry
  • Indoles / pharmacology
  • Ligands
  • Models, Molecular
  • Nuclear Magnetic Resonance, Biomolecular / methods*
  • Protein Binding
  • Recombinant Proteins / genetics
  • Recombinant Proteins / metabolism
  • Tryptophan / antagonists & inhibitors
  • Tryptophan / biosynthesis*
  • Tryptophan / chemistry

Substances

  • Escherichia coli Proteins
  • Hydrocarbons, Fluorinated
  • Indoles
  • Ligands
  • Recombinant Proteins
  • Fluorine
  • Tryptophan