Abstract
Hepatotoxicity is the most common cause of fulminant hepatic failure in the United States and the main indication for market withdrawal of drugs. This condition has been increasingly recognized as a problem of enormous medical, financial legal, and regulatory importance. It is in context of this heightened awareness of hepatotoxicity, particularly associated with new high profile drugs, that the authors reviews the published data regarding liver injury related to a novel group of asthma drugs.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Adult
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Aged
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Anti-Asthmatic Agents / adverse effects*
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Anti-Asthmatic Agents / therapeutic use
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Asthma / drug therapy
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Chemical and Drug Induced Liver Injury / etiology*
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Female
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Humans
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Indoles
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Leukotriene Antagonists / adverse effects*
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Leukotriene Antagonists / therapeutic use
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Male
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Middle Aged
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Phenylcarbamates
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Sulfonamides
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Tosyl Compounds / adverse effects*
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Tosyl Compounds / therapeutic use
Substances
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Anti-Asthmatic Agents
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Indoles
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Leukotriene Antagonists
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Phenylcarbamates
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Sulfonamides
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Tosyl Compounds
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zafirlukast