Examination of 191 specimens of Chiroptera in Osh Province of Kyrgyzstan yielded 1 strain of lyssavirus from Myotis blythi, the isolate not belonging to serotype 1. The virus was designated Aravan by the area of its isolation. Its antigenic structure was studied using antinucleocapsid monoclonal antibodies of the Wistar Institute (Philadelphia, ISA) and Central Veterinary Laboratory of Great Britain (Waybridge, Great Britain). The paper presents its antigenic profile, brief characteristics of similarity and differences of the Aravan strain and known lyssavirus serotypes.