Abstract
3-Diazo-2-phenylpyrroles 3a-g showed antimicrobial activity against Gram-positive bacteria, whereas against Gram-negative strains the inhibitory activity is limited to derivatives 3a and 3c. The substituents at 4 and 5 positions strongly influence the inhibitory activity, but the presence of the diazo group is crucial for appearance of activity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemical synthesis*
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Anti-Bacterial Agents / pharmacology
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Chemical Phenomena
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Chemistry, Physical
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Escherichia coli / drug effects
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Pyrroles / chemical synthesis*
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Pyrroles / pharmacology
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Spectrophotometry, Ultraviolet
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Streptomyces / drug effects
Substances
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Anti-Bacterial Agents
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Pyrroles