Can colorectal cancer patients with thymidylate synthase-overexpressing liver metastases have an overall survival advantage with hepatic arterial infusion alone?

J Clin Oncol. 2003 Sep 15;21(18):3543-4; author reply 3544-5. doi: 10.1200/JCO.2003.99.075.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Antimetabolites, Antineoplastic / administration & dosage*
  • Colorectal Neoplasms / mortality
  • Colorectal Neoplasms / pathology*
  • Disease Progression
  • Floxuridine / administration & dosage*
  • Fluorouracil / administration & dosage*
  • Hepatic Artery
  • Humans
  • Infusions, Intra-Arterial
  • Liver Neoplasms / drug therapy*
  • Liver Neoplasms / genetics
  • Liver Neoplasms / secondary*
  • Prognosis
  • Survival Rate
  • Thymidylate Synthase / biosynthesis*
  • Thymidylate Synthase / genetics

Substances

  • Antimetabolites, Antineoplastic
  • Floxuridine
  • Thymidylate Synthase
  • Fluorouracil