N-(2-hydroxy-5-carboxy-benzyliden)-4-substituted anilines and their methyl esters: synthesis and antimicrobial activity

M V Diurno; O Mazzoni; E Piscopo; A Bolognese

N-(2-hydroxy-5-carboxy-benzyliden)-4-substituted anilines and their methyl esters: synthesis and antimicrobial activity

Farmaco. 1992 Sep;47(9):1189-95.

Authors

M V Diurno¹, O Mazzoni, E Piscopo, A Bolognese

Affiliation

¹ Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli Federico II, Italy.

PMID: 1300124

Abstract

The N-(2-hydroxy-5-carboxy-benzyliden)-4-substituted anilines (1-6) and the corresponding 5-carbomethoxy derivatives (7-12) were synthesized and characterized. Antimicrobial and antifungal activity was tested against Gram+ and Gram- bacteria and Fungi.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aniline Compounds / chemical synthesis*
Aniline Compounds / pharmacology
Anti-Bacterial Agents
Anti-Infective Agents / chemical synthesis*
Anti-Infective Agents / pharmacology
Antifungal Agents / pharmacology
Bacteria / drug effects
Fungi / drug effects
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests

Substances

Aniline Compounds
Anti-Bacterial Agents
Anti-Infective Agents
Antifungal Agents