Circulating concentrations of fetal fibronectin do not reflect reduced trophoblastic invasion in preeclamptic pregnancies

Am J Obstet Gynecol. 1992 Aug;167(2):496-7. doi: 10.1016/s0002-9378(11)91436-7.

Abstract

This prospective, nested, case-control study investigated whether maternal plasma fetal fibronectin reflects reduced trophoblastic invasion at 16 to 20 weeks in women who later have preeclampsia. Concentrations of fetal fibronectin were 8.7 +/- 2.6 micrograms/ml in women with preeclampsia and 8.1 +/- 2.5 micrograms/ml in matched controls (p greater than 0.5). These results are discussed.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Case-Control Studies
  • Female
  • Fetal Blood*
  • Fibronectins / blood*
  • Humans
  • Neoplasm Invasiveness
  • Osmolar Concentration
  • Pre-Eclampsia / complications*
  • Pregnancy
  • Prospective Studies
  • Reference Values
  • Trophoblastic Neoplasms / complications
  • Trophoblastic Neoplasms / pathology*

Substances

  • Fibronectins