Structure and biological effects of lipid modifications on proteins

Curr Opin Cell Biol. 1992 Aug;4(4):629-36. doi: 10.1016/0955-0674(92)90082-n.

Abstract

Both the prevalence of lipid modifications of proteins and their importance for protein function and cellular localization have been widely observed. The advances made during the past year in defining the enzymology of lipid addition and in understanding the biological consequences of these modifications on protein function are discussed.

Publication types

  • Review

MeSH terms

  • Acyltransferases / metabolism
  • Animals
  • Humans
  • Lipids / biosynthesis
  • Lipids / physiology*
  • Phospholipids / metabolism
  • Protein Prenylation / physiology
  • Protein Processing, Post-Translational / physiology*
  • Proteins / metabolism*

Substances

  • Lipids
  • Phospholipids
  • Proteins
  • Acyltransferases
  • glycylpeptide N-tetradecanoyltransferase