(R)-2-(3-mercapto-2(S)-methyl-1-oxo-propoxy)-3-(methylthio)propanoic acid, the first ultra-short-acting angiotensin converting enzyme inhibitor

J Med Chem. 1992 Oct 2;35(20):3718-20. doi: 10.1021/jm00098a019.

Authors

A J Baxter¹, R D Carr, S C Eyley, L Fraser-Rae, C Hallam, S T Harper, P A Hurved, S J King, P Meghani

Affiliation

¹ Department of Medicinal Chemistry, Pharmaceutical Division, Research and Development Laboratories, Loughborough, Leicestershire, United Kingdom.

PMID: 1433185
DOI: 10.1021/jm00098a019

No abstract available

MeSH terms

Angiotensin-Converting Enzyme Inhibitors / chemical synthesis*
Animals
Captopril / analogs & derivatives*
Humans
Hydrolysis
Propionates / chemical synthesis*
Propionates / pharmacology
Rats
Structure-Activity Relationship

Substances

Angiotensin-Converting Enzyme Inhibitors
Propionates
FPL 66564
Captopril