Familial non-diabetic necrobiosis lipoidica

Australas J Dermatol. 1992;33(1):31-4. doi: 10.1111/j.1440-0960.1992.tb00049.x.

Abstract

Necrobiosis lipoidica (NL) is a cutaneous disorder with distinctive clinical and morphologic characteristics. It is associated with diabetes mellitus in two thirds of cases. The aetiology and pathogenesis of NL are unknown but familial cases of NL seem to be extremely rare. We report the occurrence of NL in two sisters with normal glucose tolerance.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biopsy
  • Blood Glucose / metabolism
  • Female
  • Humans
  • Leg / pathology
  • Middle Aged
  • Necrobiosis Lipoidica / blood
  • Necrobiosis Lipoidica / genetics*
  • Necrobiosis Lipoidica / pathology

Substances

  • Blood Glucose