Microbiologic characteristics, serologic responses, and clinical manifestations in severe acute respiratory syndrome, Taiwan

Emerg Infect Dis. 2003 Sep;9(9):1163-7. doi: 10.3201/eid0909.030367.

Abstract

The genome of one Taiwanese severe acute respiratory syndrome-associated coronavirus (SARS-CoV) strain (TW1) was 29,729 nt in length. Viral RNA may persist for some time in patients who seroconvert, and some patients may lack an antibody response (immunoglobulin G) to SARS-CoV <21 days after illness onset. An upsurge of antibody response was associated with the aggravation of respiratory failure.

MeSH terms

  • Adult
  • Antibodies, Viral / isolation & purification
  • Communicable Diseases, Emerging / epidemiology
  • Communicable Diseases, Emerging / immunology
  • Communicable Diseases, Emerging / physiopathology*
  • Female
  • Genome, Viral*
  • Humans
  • Male
  • Middle Aged
  • Reverse Transcriptase Polymerase Chain Reaction
  • Severe Acute Respiratory Syndrome / epidemiology
  • Severe Acute Respiratory Syndrome / immunology
  • Severe Acute Respiratory Syndrome / physiopathology*
  • Severe acute respiratory syndrome-related coronavirus / genetics*
  • Severe acute respiratory syndrome-related coronavirus / immunology
  • Severe acute respiratory syndrome-related coronavirus / isolation & purification
  • Taiwan / epidemiology

Substances

  • Antibodies, Viral