Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change

Angew Chem Int Ed Engl. 2003 Oct 6;42(38):4640-3. doi: 10.1002/anie.200250653.
No abstract available

MeSH terms

  • Carcinoma, Small Cell / drug therapy
  • Carcinoma, Small Cell / pathology
  • Cell Division / drug effects
  • Cell Line, Tumor
  • Doxorubicin / administration & dosage
  • Doxorubicin / pharmacokinetics
  • Doxorubicin / pharmacology
  • Doxorubicin / therapeutic use
  • Drug Delivery Systems / instrumentation*
  • Drug Delivery Systems / methods*
  • Humans
  • Hydrogen-Ion Concentration
  • Micelles*
  • Polymers / chemistry*
  • Time Factors

Substances

  • Micelles
  • Polymers
  • Doxorubicin