Malignant hypertension and cerebral haemorrhage in Seckel syndrome

Eur J Pediatr. 2003 Dec;162(12):860-2. doi: 10.1007/s00431-003-1310-z. Epub 2003 Oct 15.

Abstract

Seckel syndrome is an autosomal recessive condition with severe short stature and facial and neurological anomalies. Intracranial haemorrhage, due to rupture of a cerebral aneurysm, is a very rare complication of this syndrome. Malignant hypertension may play an important role in the aetiology of the aneurysm and early detection is essential in order to prevent organ damage.

Conclusion: we report a new case of Seckel syndrome associated with malignant hypertension and cerebral haemorrhage.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abnormalities, Multiple*
  • Aneurysm, Ruptured / etiology
  • Cerebral Hemorrhage / etiology*
  • Child
  • Dwarfism / complications*
  • Humans
  • Hypertension, Malignant / etiology*
  • Intracranial Aneurysm / etiology
  • Male
  • Microcephaly / complications*
  • Syndrome