Abstract
The bicyclic 3'-O,5'-C-methylene-linked and 2'-O,5'-C-methylene-linked 5-azacytidine derivatives were readily synthesized from 1,2;5,6-di-O-isopropylidene-D-glucose and evaluated against several cancer cell lines.
MeSH terms
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Antineoplastic Agents / chemical synthesis*
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Antineoplastic Agents / chemistry
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Azacitidine / analogs & derivatives*
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Azacitidine / chemical synthesis*
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Azacitidine / chemistry
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Cell Survival / drug effects
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Drug Screening Assays, Antitumor
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Humans
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Indicators and Reagents
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Molecular Structure
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Tumor Cells, Cultured
Substances
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Antineoplastic Agents
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Indicators and Reagents
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Azacitidine