18F-FDG PET: early postoperative period of oro-maxillo-facial flaps

Nuklearmedizin. 2003 Oct;42(5):210-4.

Abstract

Aim: We addressed the feasibility of FDG-PET to differentiate between viability and non-viability in the immediate postoperative assessment of flaps (autologous microvascular anastomosed pedicled flaps) in oro-maxillo-facial surgery.

Methods: 3-7 days after surgery, FDG-PET was done in 38 patients who had received flaps for re-construction of the mandible after partial resection. The studies were done on a dedicated full ring PET-scanner (ECAT EXACT HR+, Siemens/CTI). Acquisition started between 60 and 80 min post injection. The findings of the soft tissue component of the flaps were grouped using a three point scale: (I) no defect, (II) small defects, (III) one large defect. The results of PET were compared with the clinical course for at least 3 months.

Results: "No defect" on the FDG-PET study identified vi-ability of the flap and predicted normal clinical follow-up (22/38 patients). "Small defects" visualized areas of decreased perfusion and decreased glucose metabolism indicating risk of non-viability (13/38 patients); adapt-ing the postsurgical management led to delayed but uncomplicated healing of the flaps in these patients. "One large defect" demonstrated early necrosis of the flap (3/38 patients). After removal and replacement of this necrotic portion of the flap the second FDG-PET scan of these 3 patients demonstrated the uncomplicated post-operative healing.

Conclusion: FDG-PET facilitated the assessment of viability and non viability of flaps in the immediate postsurgical period, and demonstrated the usefulness of FDG-PET for postoperative care and prognosis.

MeSH terms

  • Adult
  • Aged
  • Blood Glucose / metabolism
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Male
  • Mandibular Neoplasms / surgery*
  • Maxilla / diagnostic imaging
  • Maxilla / surgery*
  • Middle Aged
  • Mouth / diagnostic imaging
  • Mouth / surgery*
  • Plastic Surgery Procedures
  • Postoperative Period*
  • Radiopharmaceuticals*
  • Surgical Flaps*
  • Tomography, Emission-Computed*
  • Wound Healing

Substances

  • Blood Glucose
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18