Differentiation of a primitive neuroectodermal tumor into a benign ganglioglioma

J Neurooncol. 1992 Nov;14(3):237-41. doi: 10.1007/BF00172599.

Abstract

We describe a case of cerebellar neuroblastoma with histologic documentation of maturation into a ganglioglioma sixteen months later. Only chemotherapy was administered following the initial surgery and the child is well and disease-free three years following her final surgical procedure. The outcome of this patient supports previous hypotheses that the cerebellar neuroblastoma may be a less malignant tumor than its other primitive neuroectodermal posterior fossa counterparts. Furthermore, this case suggests a role for second-look surgery in the management of selected pediatric brain tumors.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cell Differentiation
  • Cerebellar Neoplasms / drug therapy
  • Cerebellar Neoplasms / pathology*
  • Cerebellar Neoplasms / surgery
  • Combined Modality Therapy
  • Female
  • Humans
  • Infant
  • Neuroblastoma / drug therapy
  • Neuroblastoma / pathology*
  • Neuroblastoma / surgery
  • Reoperation