Abstract
A 40-year-old female visited our hospital with general malaise. She was diagnosed with gastric carcinoma with multiple skin, bone, and bilateral ovary metastases. Chemotherapy with 5-FU (1,000 mg/w) and cisplatin (10 mg/w) was performed in the outpatient clinic. Two years after the initial diagnosis, CEA was elevated. She then was given chemotherapy of CPT-11 (40 mg/w) in the outpatient clinic after 1 cycle of combined chemotherapy of CPT-11 and cisplatin. She died 38 months after the initial diagnosis. Weekly 5-FU/CDDP or low-dose CPT-11 appear to be effective for such a gastric carcinoma with systemic metastases without impairing quality of life.
MeSH terms
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Adenocarcinoma / drug therapy*
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Adenocarcinoma / secondary
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Adult
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Bone Neoplasms / drug therapy
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Bone Neoplasms / secondary*
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Camptothecin / administration & dosage
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Camptothecin / analogs & derivatives*
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Cisplatin / administration & dosage
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Drug Administration Schedule
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Female
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Fluorouracil / administration & dosage
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Humans
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Irinotecan
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Ovarian Neoplasms / drug therapy
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Ovarian Neoplasms / secondary*
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Prognosis
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Quality of Life
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Skin Neoplasms / drug therapy
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Skin Neoplasms / secondary*
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Stomach Neoplasms / drug therapy*
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Stomach Neoplasms / pathology
Substances
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Irinotecan
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Cisplatin
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Fluorouracil
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Camptothecin