Abstract
A low plasma prolactin concentration has been reported to be associated with an increased risk of subsequent relapse in patients with schizophrenia. Prolactin concentration was measured in samples from stable schizophrenic men who were outpatients just prior to neuroleptic withdrawal. No relationship between prolactin concentration and time to subsequent relapse was found. Prolactin concentration may predict time to relapse only in populations characterized by specific demographic features or medication history.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Administration, Oral
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Adult
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Brain / physiopathology
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Dopamine / physiology
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Fluphenazine / administration & dosage
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Fluphenazine / adverse effects
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Haloperidol / administration & dosage
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Haloperidol / adverse effects
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Humans
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Male
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Prolactin / blood*
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Psychiatric Status Rating Scales
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Recurrence
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Risk Factors
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Schizophrenia / diagnosis
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Schizophrenia / drug therapy
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Schizophrenia / physiopathology*
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Schizophrenic Psychology*
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Substance Withdrawal Syndrome / diagnosis
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Substance Withdrawal Syndrome / physiopathology
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Substance Withdrawal Syndrome / psychology
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Trifluoperazine / administration & dosage
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Trifluoperazine / adverse effects
Substances
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Trifluoperazine
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Prolactin
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Haloperidol
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Fluphenazine
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Dopamine