Development of a high-throughput screen for protein catalysts: application to the directed evolution of antibody aldolases

Angew Chem Int Ed Engl. 2003 Dec 15;42(48):5971-3. doi: 10.1002/anie.200352117.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aldehyde-Lyases / chemistry*
  • Aldehyde-Lyases / genetics
  • Aldehyde-Lyases / metabolism
  • Antibodies, Catalytic / chemistry*
  • Antibodies, Catalytic / genetics
  • Antibodies, Catalytic / metabolism
  • Catalysis
  • Complementarity Determining Regions
  • Directed Molecular Evolution*
  • Electrophoresis, Polyacrylamide Gel
  • Enzyme-Linked Immunosorbent Assay
  • Proteins / chemistry*

Substances

  • Antibodies, Catalytic
  • Complementarity Determining Regions
  • Proteins
  • Aldehyde-Lyases