Posttranscriptional generation of macromolecular complexes

Mol Cell. 2003 Dec;12(6):1347-9. doi: 10.1016/s1097-2765(03)00496-9.

Abstract

Discrete classes of mRNAs that encode functionally related proteins are associated with sequence-specific RNA-binding proteins in yeast and mammalian cells. recently reported that pre-mRNAs encoding components of inhibitory synapses are bound to neuron-specific Nova RNA-binding proteins.

MeSH terms

  • Animals
  • Antigens, Neoplasm*
  • Gene Expression Regulation
  • Macromolecular Substances*
  • Nerve Tissue Proteins / metabolism
  • Neuro-Oncological Ventral Antigen
  • Neurons / metabolism
  • RNA Processing, Post-Transcriptional*
  • RNA, Messenger / metabolism*
  • RNA-Binding Proteins / metabolism
  • Receptors, Cell Surface / metabolism
  • Synapses / physiology

Substances

  • Antigens, Neoplasm
  • Macromolecular Substances
  • Nerve Tissue Proteins
  • Neuro-Oncological Ventral Antigen
  • RNA, Messenger
  • RNA-Binding Proteins
  • Receptors, Cell Surface