Exhaled nitric oxide in chronically ventilated preterm infants

O Williams; R Y Bhat; P Cheeseman; G F Rafferty; S Hannam; A Greenough

doi:10.1136/fn.89.1.f88

Exhaled nitric oxide in chronically ventilated preterm infants

Arch Dis Child Fetal Neonatal Ed. 2004 Jan;89(1):F88-9. doi: 10.1136/fn.89.1.f88.

Authors

O Williams¹, R Y Bhat, P Cheeseman, G F Rafferty, S Hannam, A Greenough

Affiliation

¹ Children Nationwide Regional Neonatal Intensive Care Centre, 4th floor Ruskin Wing, King's College Hospital, London SE5 9RS, UK.

Abstract

Exhaled nitric oxide (eNO) levels were measured in eight ventilated infants, mean gestational age 25.8 (SD 1.7) weeks and postnatal age 55 (SD 39) days, before and after three days of dexamethasone treatment. The eNO levels fell from a mean of 6.5 (SD 3.4) to 4.2 (SD 2.6) parts per billion (p = 0.031) and the mean supplementary oxygen levels from 62% to 45% (p = 0.0078).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Inflammatory Agents / therapeutic use*
Carbon Dioxide / physiology
Chronic Disease
Dexamethasone / therapeutic use*
Humans
Infant, Newborn
Infant, Premature, Diseases / physiopathology*
Lung Diseases / physiopathology*
Nitric Oxide / physiology*
Oxygen / physiology
Respiration, Artificial / methods

Substances

Anti-Inflammatory Agents
Carbon Dioxide
Nitric Oxide
Dexamethasone
Oxygen