tPA and proteolysis in the neurovascular unit

Stroke. 2004 Feb;35(2):354-6. doi: 10.1161/01.STR.0000115164.80010.8A.
No abstract available

Publication types

  • Editorial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Astrocytes / drug effects*
  • Astrocytes / enzymology
  • Cerebral Hemorrhage / chemically induced
  • Cerebral Hemorrhage / prevention & control
  • Endothelium, Vascular / drug effects*
  • Endothelium, Vascular / enzymology
  • Enzyme Inhibitors / pharmacology
  • Fibrinolysis / drug effects
  • Humans
  • Matrix Metalloproteinases / drug effects
  • Matrix Metalloproteinases / metabolism
  • Neurons / drug effects*
  • Neurons / enzymology
  • Peptide Hydrolases / drug effects
  • Peptide Hydrolases / metabolism*
  • Stroke / drug therapy*
  • Stroke / physiopathology
  • Tissue Plasminogen Activator / adverse effects
  • Tissue Plasminogen Activator / therapeutic use*
  • Up-Regulation / drug effects

Substances

  • Enzyme Inhibitors
  • Peptide Hydrolases
  • Tissue Plasminogen Activator
  • Matrix Metalloproteinases