[Cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy]

Med Clin (Barc). 2004 Mar 6;122(8):298-300. doi: 10.1016/s0025-7753(04)74214-1.
[Article in Spanish]

Abstract

Background and objective: Our goal was to assess the main characteristics of cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy (HAART).

Patients and method: Retrospective analysis of the clinico-epidemiological characteristics of 16 HIV-infected patients treated with HAART who had suffered a cardiovascular event from a 1,459 patients' cohort.

Results: Clinical presentation of cardiovascular disease was an acute coronary syndrome in 12 cases, ischemic stroke in 2 and peripheral vascular disease in 2. Patients included in the study had a mean of 3.2 cardiovascular risk factors, smoking and low HDL levels being the more prevalent risk factors. Eight (50%, 95% CI, 25-75%) patients fulfilled the criteria of metabolic syndrome. The mean CD4 count was 548 x 10(6)/l.

Conclusions: HIV-infected patients on HAART ha-ve a high cardiovascular risk. A strict management of modifiable risk factors must be warranted in these patients.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Antiretroviral Therapy, Highly Active*
  • Cardiovascular Diseases / complications*
  • Cardiovascular Diseases / prevention & control
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • HIV-1*
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors