[Current concepts and recent developments of laser ablation in tumor therapy]

Radiologe. 2004 Apr;44(4):320-9. doi: 10.1007/s00117-004-1034-8.
[Article in German]

Abstract

Purpose: The purpose of this paper is to present technical innovations and clinical results of percutaneous interventional laser ablation of tumors using new techniques. METHODS; Laser ablation was performed in 182 patients (liver tumors: 131, non hepatic tumors-bone, lung, others: 51) after interdisciplinary consensus was obtained. The procedure was done using a combination of imaging modalities (CT/MRI, CT/US) or only closed high field MRI (1.5 T). All patients received an MRI-scan immediately after laser ablation.

Results: In 90.9% of the patients with liver tumors, a complete ablation was achieved. Major events occurred in 5.4%. The technical success rate of laser ablation in non-hepatic tumors was high, clinical results differed depending on the treated organ.

Conclusions: The treatment of tumors of the liver and other organs up to 5 cm by laser ablation was a safe procedure with a low rate of complications and side effects. Image guidance by MRI is advantageous for precise tumor visualization in all dimensions, therapy monitoring, and control of laser ablation results.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Female
  • Humans
  • Hyperthermia, Induced / methods*
  • Hyperthermia, Induced / trends
  • Laser Therapy / methods*
  • Laser Therapy / trends
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / therapy*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Neoplasms / diagnosis
  • Neoplasms / diagnostic imaging
  • Neoplasms / therapy
  • Organ Specificity
  • Therapy, Computer-Assisted / methods*
  • Tomography, X-Ray Computed / methods*
  • Treatment Outcome
  • Ultrasonography / methods*