Computed tomography (CT) evaluation of breast cancer patients with osteolytic bone metastases undergoing palliative radiotherapy--a feasibility study

Edward Chow; Lori Holden; Joel Rubenstein; Monique Christakis; Katharina Sixel; Marjan Vidmar; Joel Finkelstein; Charles Hayter; Andrew Loblaw; Rebecca Wong; Ewa Szumacher; Cyril Danjoux

doi:10.1016/j.radonc.2004.01.009

Computed tomography (CT) evaluation of breast cancer patients with osteolytic bone metastases undergoing palliative radiotherapy--a feasibility study

Radiother Oncol. 2004 Mar;70(3):291-4. doi: 10.1016/j.radonc.2004.01.009.

Authors

Edward Chow¹, Lori Holden, Joel Rubenstein, Monique Christakis, Katharina Sixel, Marjan Vidmar, Joel Finkelstein, Charles Hayter, Andrew Loblaw, Rebecca Wong, Ewa Szumacher, Cyril Danjoux

Affiliation

¹ Rapid Response Radiotherapy Program and Bone Metastases Site Group, Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5.

PMID: 15064015
DOI: 10.1016/j.radonc.2004.01.009

Abstract

Twenty-five patients with osteolytic metastases had computed tomography (CT) scans before and 3 months after palliative radiotherapy. The median % density change following single 8Gy, 20Gy/5#, 30Gy/10# were: 128 (range 98-255), 141 (79-342), and 145 (65-235), respectively. It is feasible to evaluate remineralization of osteolytic lesions with palliative radiotherapy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Aged, 80 and over
Bone Density
Bone Neoplasms / diagnostic imaging*
Bone Neoplasms / radiotherapy
Bone Neoplasms / secondary*
Breast Neoplasms / pathology*
Feasibility Studies
Humans
Middle Aged
Osteolysis / diagnostic imaging
Palliative Care*
Radiotherapy Dosage
Tomography, X-Ray Computed*