Abstract
A 28-year-old man, who had undergone right orchiectomy and prophylactic irradiation for stage I seminoma 6 years ago, developed left testicular tumor. Since the secondary tumor was localized in the lower pole of the testis, partial orchiectomy was performed with an attempt to preserve the testicular function. The pathological finding of the surgical specimen was a mixed type testicular tumor consisting of seminoma, embryonal carcinoma and teratoma elements. Postoperative chemotherapy with 3 courses of BEP regimen resulted in azoospermia, but the impaired spermatogenesis recovered to a normal range within 18 months with no evidence of tumor recurrence and his wife delivered a healthy baby 2 years later. For the synchronous or metachronous bilateral testicular tumors, the combination of organ sparing surgery and chemotherapy could be a treatment of choice.
Publication types
-
Case Reports
-
English Abstract
-
Review
MeSH terms
-
Adult
-
Antineoplastic Combined Chemotherapy Protocols / administration & dosage
-
Antineoplastic Combined Chemotherapy Protocols / adverse effects
-
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
-
Bleomycin / administration & dosage
-
Bleomycin / adverse effects
-
Carcinoma, Embryonal / physiopathology
-
Carcinoma, Embryonal / surgery*
-
Cisplatin / administration & dosage
-
Cisplatin / adverse effects
-
Combined Modality Therapy
-
Etoposide / administration & dosage
-
Etoposide / adverse effects
-
Fertility*
-
Humans
-
Male
-
Neoplasms, Second Primary*
-
Oligospermia / chemically induced
-
Orchiectomy / methods*
-
Seminoma / physiopathology
-
Seminoma / surgery*
-
Teratoma / surgery*
-
Testicular Neoplasms / physiopathology
-
Testicular Neoplasms / surgery*
-
Testis / physiology
-
Testis / physiopathology
-
Treatment Outcome
Substances
-
Bleomycin
-
Etoposide
-
Cisplatin