Seizures as the presenting symptom of brain tumours in children

Seizure. 2004 Mar;13(2):108-12. doi: 10.1016/s1059-1311(03)00083-9.

Abstract

Seizures were the presenting clinical symptom in 10 (12%) of 81 consecutive children with a primary brain tumour treated in a tertiary paediatric oncology unit over 5 years. Nine patients experienced partial seizures, and in seven a waking electroencephalogram showed focal or lateralising abnormalities. Astrocytoma was the most common tumour histology. The delay in tumour diagnosis from the onset of seizures ranged from 2 weeks to 2 years with a mean of 6 months. Complete resection of the tumour was the only treatment in three patients and four underwent resection followed by radiotherapy and/or chemotherapy. Two patients died. Three patients became seizure free receiving no antiepileptic medication and the remaining five showed a 50-80% reduction in seizures between 2 and almost 5 years following treatment.

MeSH terms

  • Brain Neoplasms / complications*
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / pathology
  • Child, Preschool
  • Diagnosis, Differential
  • Electroencephalography
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Retrospective Studies
  • Seizures / diagnosis*
  • Seizures / etiology*