Genomic Object Net: II. Modelling biopathways by hybrid functional Petri net with extension

Appl Bioinformatics. 2003;2(3):185-8.

Abstract

This paper demonstrates how to create an HFPNe (hybrid functional Petri net with extension) model, using the lac operon gene regulatory mechanism and glycolytic pathway as an example. Using this example, readers can then model other biopathways of interest. Simulations of the HFPNe model were performed using the software package Genomic Object Net.

Publication types

  • Evaluation Study

MeSH terms

  • Computer Simulation*
  • Documentation
  • Escherichia coli / genetics
  • Escherichia coli / metabolism*
  • Gene Expression Regulation, Bacterial / physiology*
  • Glycolysis / physiology*
  • Lac Operon / genetics*
  • Models, Biological*
  • Multienzyme Complexes / genetics
  • Multienzyme Complexes / metabolism
  • Signal Transduction / physiology
  • Software*
  • User-Computer Interface*

Substances

  • Multienzyme Complexes