ERM proteins of the lens

J Cell Biochem. 2004 Jun 1;92(3):626-30. doi: 10.1002/jcb.20062.

Abstract

Ezrin and radixin and protein 4.1 were detected in the lens of the eye. These proteins were mainly present in the young elongating cortical fiber cells and localized to the plasma membranes. Moesin was not detected. Ezrin, radixin, and protein 4.1 provide another means whereby actin is linked to the plasma membrane in addition to the known adherens junctions in the lens.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Blood Proteins / metabolism*
  • Blotting, Western
  • Cats
  • Cattle
  • Cell Membrane / metabolism
  • Chickens
  • Cytoskeletal Proteins / metabolism*
  • Dogs
  • Electrophoresis, Polyacrylamide Gel
  • Humans
  • Lens, Crystalline / chemistry
  • Lens, Crystalline / cytology
  • Lens, Crystalline / metabolism*
  • Membrane Proteins / metabolism*
  • Microfilament Proteins / metabolism*
  • Phosphoproteins / metabolism*
  • Rats

Substances

  • Blood Proteins
  • Cytoskeletal Proteins
  • Membrane Proteins
  • Microfilament Proteins
  • Phosphoproteins
  • ezrin
  • moesin
  • radixin